Modeling Oxygen concentration in skeletal muscle
نویسندگان
چکیده
منابع مشابه
Reactive Oxygen Species in Skeletal Muscle Signaling
Generation of reactive oxygen species (ROS) is a ubiquitous phenomenon in eukaryotic cells' life. Up to the 1990s of the past century, ROS have been solely considered as toxic species resulting in oxidative stress, pathogenesis and aging. However, there is now clear evidence that ROS are not merely toxic species but also-within certain concentrations-useful signaling molecules regulating physio...
متن کاملModeling of active skeletal muscle
In this contribution a continuum constitutive model for the passive and active mechanical response of skeletal muscle tissue is presented. Within the verification of the model’s predictive capabilities and its numerical behaviour, a benchmark simulation is introduced. The presented model allows for simulation of complex soft tissue structures and their interactions. In a numerical example, an a...
متن کاملImpaired skeletal muscle microvascular function and increased skeletal muscle oxygen consumption in severe falciparum malaria.
BACKGROUND Organ dysfunction and tissue hypoxia in severe falciparum malaria result from an imbalance between oxygen delivery and demand. In severe malaria, microvascular obstruction from parasite sequestration decreases oxygen delivery. However, host microvascular function (defined as the capacity to increase oxygen delivery in response to ischemia) and oxygen consumption have not been assesse...
متن کاملOxygen tension distribution in postcapillary venules in resting skeletal muscle.
We tested the hypothesis that blood flow is distributed among capillary networks in resting skeletal muscle in such a manner as to maintain uniform end-capillary PO2. Oxygen tension in venules draining two to five capillaries was obtained by using the phosphorescence decay methodology in rat spinotrapezius muscle. For 64 postcapillary venules among 18 networks in 10 animals, the mean PO2 was 30...
متن کاملBlood Flow, Blood Oxygen Tension, Oxygen Uptake, and Oxygen Transport in Skeletal Muscle.
STAINSBY, WENDELL N., AND ARTHUR B. OTIS. BZoodLfTow, blood oxygen tension, oxygen uptake, and oxygen transport in skeletal muscle. Am. J. Physiol. 206(4) : 858-866. rg64.-The effect of changes in blood flow and of blood oxygen tension on oxygen uptake of the in situ gastrocnemius-plantaris muscle group of the dog was examined. Oxygen uptake by resting muscle was not altered by changes in blood...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Mathematical and Computer Modelling
سال: 1997
ISSN: 0895-7177
DOI: 10.1016/s0895-7177(97)00147-7